Dissolving microneedle technology can be extensively applied in the areas of cosmetology and skincare products. Compared with traditional daub-type skincare products, dissolving microneedle technology can deliver effective ingredients to the skin where they are needed, complemented by absorption efficiency that is exponentially higher than that of traditional skincare products. Therefore, the dissolving microneedle patch can achieve effect similar to that of hyaluronic acid injection and hydro-lifting performed in beauty salon. Through transdermal drug delivery, this technology can overcome the problem of low active ingredient absorption efficiency prevalent in traditional skincare, actualizing the painless transdermal absorption of macromolecular active ingredients such as hyaluronic acid. Creawe has blazed a new trail in the skincare industry by combining new transdermal drug delivery methods with scientific formula ingredients, and a myriad of dissolving microneedle skincare patches with more skincare effects will be launched soon.

In the field of medical devices, dissolving microneedle can be used to help transdermal absorption of drugs by using micro pore passages produced microneedle that have penetrated the cuticle to facilitate delivery of the medicine directly to the deep epidermal layer without reaching the nerve endings of the dermis. Therefore, the delivered drug can achieve efficient osmotic conduction without causing pain or skin injury. Dissolving microneedle medical devices can also be applied in cosmetology. After the dissolving microneedle penetrates the cuticle layer of the skin, micropores will be generated on the skin surface, which can effectively improve the absorption efficiency of drugs and active ingredients, and effectively improve anti-aging performance, acne removal, chromatosis, hair loss and other problems.

Transdermal drug delivery system (TDDS) is a novel drug delivery route based on pharmaceutical properties and physicochemical methods, through which the delivered drug may pass through the skin at a certain rate and enter the human body to produce a local or whole-body treatment effect through the skin. The bottleneck in the development of transdermal delivery technology is that only a few small molecular compounds can penetrate the barrier of the epidermis, and the development of transdermal agents is limited by the small number of drugs available. Dissolving microneedle transdermal drug delivery technology can help drugs (especially macromolecular drugs) physically penetrate the cuticle layer of the skin and nullify skin penetration limitations due to drug molecule size, making this the most promising research and development prospect in the field of transdermal drug delivery.

The principle of dissolving microneedle technology is that the drugs are formed into a microneedle array with sufficient strength on the patch matrix as a drug delivery channel, so that the drug can directly penetrate the cuticle to the interior, thus possessing the advantages of both injection and transdermal delivery. Dissolving microneedle transdermal administration is noted for usage convenience, zero peak and trough phenomenon of blood concentration. In addition, dissolving microneedle can avoid and reduce toxicity and side effects and first-pass effects of drugs, as well as inactivate gastrointestinal tract. Dissolving microneedle transdermal administration is an excellent alternative to oral and injectable administration for elderly patients that have difficulty in swallowing, patients with difficulty in taking medication, and children sensitive to pains from injections.